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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1e8a9f5d5b0853ccca60c0c176229007d840128f6b55991625994fd06c1c60b' 
  AND token = 'rozCjyKETyPDEYMZoWLFUh8UFpeoMotHToI4gAHRwRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}