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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c1cf62640b22b9523fdc7789b60f76172a5afc6c1fdee05d763ac687141fc6' 
  AND token = 'q4YpGruYMeGKSdE9I57OxmSYj+WGMQNG4v+L+IQzz0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}