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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46304c235cfb4b8940f95bcb5236d94edf3b76d6e8208c69782ed3f4baf529b6' 
  AND token = 'sYxMI0CFpT7naNt98ifICFrgFXlXu4XvTPFs80cg/3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}