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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73277b62c71599098eaf524eed8c97fa35a9534c1276ef398bb5dc193f6bd11d' 
  AND token = 'Ht0igwMnl/kSCcIUfNMrYEaedF5fS2JnPJb29OCeUoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}