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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6fe01ac0c381dc3cfb96245e120fddc7070dbe0044ed78bede40e1a00607422' 
  AND token = 'd7lZ12TAxEvZzd+ybrsC/cnxrPj15kYqzZz/5sOHe7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}