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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe9099d4d9f6ba459e2599ed84dc7dab472d45862247c73914b95ed9e59c5520' 
  AND token = 'maUFf2MyPGCrbq0PR0XKICXTRmSBHsrc+efS19ixDug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}