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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec0fc0e3115a99946482cbe2c44da216e250b8da7401e0742de43df38e6d69a7' 
  AND token = 'fvU8fPZc+RleusbidqZeXBUCTs2kZ1G1OwjCq5Mi6NY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}