SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff82a5056466aa0a8dafc74784774336dbace0d88166018679d55312a439b2fd' 
  AND token = 'TanKdW42FNYECDO7MwBqx02O8uN0uvw1XrZsZxVXvuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}