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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e9c1b4bfe4b0bab3e7d4d6d18388cdf2813a625e3c278adda30f58b52ac0522' 
  AND token = 'p7US4rXPUlt7peOO+HmWV4mE4Y5smV+4/C5IHs7uGQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}