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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b440dffe5466922fd367d1341c2f66ba0a94da97a2a0233c660b1273aed2d2b6' 
  AND token = 'ELtAAJ/DJCy/NesGZ5LY0hrxmpELqj04ELJIvjc3FjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}