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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1041e355319c201471432110241454e346e5a173d7d2c6bfb147f54b336d524' 
  AND token = 'nDyEUt3wA/DZNNsEX2mLXoK0cLm7xC81BxH+QSQD8xM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}