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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82c8755e3c2f24dcc50da98cdaa794bf2a068a48c767f55900089aeac0224b38' 
  AND token = 'JRxknQS/d9rJS/xWfvEMTtjAEP8kBSg7PdJt9oNETNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}