SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222a55e8a6508e12cb722d56ef9252c067170356f466459beb1f59ed0aee1c76' 
  AND token = '198DKyuNum3a1Nv771sJToPuvc0CmSNt9Ug8P5m6iRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}