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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ccc2ab4655cc7c84c9e0a5597bd2246d642b0fbd7068f39ff33634e72177b07' 
  AND token = 'lQ+2RgPsI9Go5tLWDznWqmnXWeaK7bjmTdo9/PE0fg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}