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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bb9f72eb0ae93dc7168d1614b79ca1a5b45879f02e67409b67c0774220f5c7f' 
  AND token = 'ULtwNxc1zyXVLRQ2eKfBFLuOiR2i/AmOScNLsijMdmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}