SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '776e115de16782a9b2f1c35261251e4f20de17b80b4de15c573fa766e08f764f' 
  AND token = 'AJxxp6ZLBnNXjPUenNJ5YoD0/+8nF3yAuB25zmeyglI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}