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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522111b164636e0949f9e1d229eff6cb98f2bfaf8bb86e6b723056b74b203c6d' 
  AND token = 'Jo4LwlB7kjWBYBD4SyTXRUxntMRBR9/DnygTyN8t2oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}