SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d74cebea2c47cbbbf73aa2698e2329c618a909ab4d789cd6f104c459a6a416' 
  AND token = 'hFTndByN8pqQnKv01WzKgvoN9IqQeqOrFmkv33bvppA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}