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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ccb2fd801e9b2ba9589183bb3aad57e7d4868e59b04b82febfb86697dcc2845' 
  AND token = 'f4WqjkYZ2K9dYqcjE5gOR9+53ArejZ9FSWY7GbKUgIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}