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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6bb65d71296354252a2cc7b2843ed58cbfc7d324970e8c8478c95f95fdad40f' 
  AND token = '5X+8GaPXICXK8i5h/NS6WLK1TT9Ua0LCBHX6K6mTOjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}