SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88341526a12eb5631c274012dc357742c5ebded23a4eaac48aed9685e3be1dea' 
  AND token = 'Ip3bE1EUaYUOvyrqtMNuPwl2bD4n+7x0OLhV0rBd2cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}