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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cca30fd1b49b7b4ca23b614eff455be8865d8f16e836533139b0599a11a4d63d' 
  AND token = 'OsgPbxd3DVG18blm71PyFEdA2IHLZ9/IO3nZnWwal9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}