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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61f22526ef5b93657e02b9ad9f8da9fd8c450050f87b13a2674cb472b2d421da' 
  AND token = 'kq3R/iUemY+4gqgS7MdsX7TMV9M/Q2PJSWNgfJxRbUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}