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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1718eb5435e690302fe1680b7a3ffcfa0604e21672877a6b7eb7fd2a1648435b' 
  AND token = 'BtzAOSm+A6/i2Sq3laDQiwWzkOKIuzfAD4Hhgx6Pyqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}