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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59b0c5d81f0905ca2c963dd7a3e2a06856da89c2293483e8f360379d251a7d7f' 
  AND token = 'd8+QmJtpKIPzvyahyk1A74smrmE4SKLEPAG2v04PnPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}