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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36f7b518220c856cf508e0eeba1f8f5a1d4ca0967654e715f80cfc4147ca0e75' 
  AND token = 'v5JnlKwtq+kQ9bQSOWUr7+L4cE9WhgInB8rd4Vt+pDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}