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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52787d881037148b69843bf9267f6640ad97f99fb5842f90ab7a50b5d35b36ef' 
  AND token = '7ZrWLVgm7cO64iChrbEtQFyyfNM3zIPVXfFU+DFPeOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}