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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4c709575fc7be18af8945bc2f5ff76bab2886f94cf3548b580b3947f1e01f3f' 
  AND token = '/+pl67WtEJyleoK1hX0dC7hl1JcRvs12F9dbnpA403o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}