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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adc6cb1f49432672182318b2a69c9cc37203718b5f1b1c621dfa5e91f350c3e8' 
  AND token = 'D+HKCVXVWMUtR7VEX45oB4T9+kZmuccbBUZKm4ME78I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}