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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85a157e2f09617616fb0f30fce34d24cd9ccce308dc5fc75b5530a22c418cde7' 
  AND token = '2QK4yQd2iaoki4Idt4XN6CgLFfi6QPZq7bDQ/L+VFS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}