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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfd95fb3729e5153bb4d141a0fd7e7637c3dfc82bd4dd8064caad9e548dc19b0' 
  AND token = 'VftvrLa6lnHA5hsyGtWcOOrT67c2X/mqXe1NpqPlnfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}