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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63277fcd2c7cb38d2b9167c58f3f894d29cd6b3ff24b527874eef85b7a5888af' 
  AND token = 'h+kHoaJmEp0vVF+P2XJXrbD+tHBwsAh9XBzI80kTVHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}