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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abfff1306d29e8db6598063654d1824d12b5f83438a1f13aba523ffb4a0bd47d' 
  AND token = 'dM+/q0PE60UUFUsvQshd+d85sQtb70XqSOdL14IA/+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}