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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d0a66084ef155c8f5d7d3643a087e9ed73c2de92697a8021ec5bddf13f21c1c' 
  AND token = 'QuEEhG0gyRj6UGHIIS0eCSlByfUowJAY/MiAsSm44IU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}