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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1c5c3f85b32baa71b05b1cbff12d94b102fcfdf48b18e7325bf2c31938f4e60' 
  AND token = 'SQCdmpDFrxe0nyPExe8GwyI5C3dKMMNuDdXrQH+Hfhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}