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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2c63f89f0b94f2ed3973af00e7982813c2bd21d2b000b07bb44def61f32c3eb' 
  AND token = 'zoO7OX8MKdNriif/088U4y3yFOMR5bNzpxR9sVSCny8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}