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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c0c4509a372aeaa6cdf8017a364463bd77a79ac9c5a622ad732826f8f315ace' 
  AND token = 'KGvx1yEGIqJexif40shK/koaRM+HTI2dDox7cpuKS/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}