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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1290176b84198238a7c0cb0a254a9fd8b8c2ff0cfa6abe08b73f9c8503862070' 
  AND token = 'Y5uUG0WexjMPQYA0H02bdkCrn5NZsM9IgQPQSOCUA2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}