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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '187b74977695bd6a15a801e12fc0aaac9bc249aeeb71b2a1566b3bd1c4d6ff06' 
  AND token = 'yThiHXMkM200QkYCJ9NgjUAUn+yp0waColN9X9A7hxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}