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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5755c2abb79e097a84ea8bd006b8ba4f3cf45d8a55e6a8383950e9f748a9d935' 
  AND token = '89a/KJAC5SuDnZVVPN+EUq3P7Sg/xfZ7+4r27lvwhm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}