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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e24e9a1bbac00f2fe7024c1ad8ced0da72f0af868e2777196215e0b8ae6ca54b' 
  AND token = 'uiroaO0RKkhQXJpIkQK7cn8PPQPI2QtgfKOKDen6viY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}