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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e822c6e3993a5d37afaae82cf1d839b615a271f955d9db8ca029d8ed9cc4b7e2' 
  AND token = 'eVkL5eMf+7AAGgBWX9DXgzMreEKauMDd9IY1GoYag6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}