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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5001674c264af818f57779450cb8f02ede05b77923e323feb525d144dd9826f7' 
  AND token = 'Lsy9Rn2+RRYmPgRU01iIkzBs/muhgro/lBhWeC/6/yI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}