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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6637aeedbb062f41122e3c948bc2a00690ec09151379089ccf8ef3fb57b09db8' 
  AND token = 'D6ZVnI+igqAk9jjUGwkqM7f59cy/quqiIHduA/agqjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}