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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97b6e1b3620e57b897ecaedac5b0794b139b12ee18887eb232209d74f8f72a06' 
  AND token = 'eprE7DbyF5pa3fLHf/7wDhqvfils3EmFxOwdc47302E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}