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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fcc81afb02e722f1dc3afb8d8191b0cc70082ac32c086a13b38cef3035ca4b6' 
  AND token = 'zi0pWKEutTrYpmaWr+VDQ7Bos/7Xa2INDw8fEq4VSGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}