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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce52b3c334bdacba0c275c6fd75f39127426ef43b62a5504e55316cb7485faca' 
  AND token = 'Uvr/GPzZc+++8NcIzjujfoViO719gur6/6op2VsbtZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}