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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '377a24f8a7e23dbdaddccf418d10f81433c4a0a302a1634ee62bd9b3c620b071' 
  AND token = 'fJPiasooOPnqdNueRpahcqAomfIFVn4XzFTbLG+LzhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}