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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37cc83e84fc8773f5affa94f0fbb0763f479f47f966755af7a0c9977f337c424' 
  AND token = '3utVH6vQhSfYT1/FopzxhXQSl9NPM8xmGUy4T/3zB40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}