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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f139656e695bd2c904a8720d4b0149353f649b8f9e48522dab8b427f203d59b' 
  AND token = '78cdubHBB/B0zOia7cPAv03+niiVOb784/pm+1VBtIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}